| 摘要 |
There is provided a cassette-implant for implantation in the body of mammals, comprising a housing with at least one removable and replaceable wall portion, with inlet and with outlet means for the supply of a liquid nutrient, and which cassette contains a thin disk or tablet formed member, or a plurality of stacked discs which contain one or more distinct spaces, each of which is adapted to receive a signal individual cell which is cultivated in such space, at least one of the walls being transparent; and a method for the controlled cultivation of cells by means of such cassette, while said cassette is implanted inside the body of mammals, but said cultivation being continued at will on the outside of the body while said cassette is supplied with natural or artificial nutrient media, being connected to the living body or only to a source of nutrient, said method providing means for the evaluation of the influence of various substances on the growth of a single cell, or on the growth of a number of single cells, separated from each other, and each positioned in a suitable individual receptacle for such cell, while the cassette is connected with a supply of nutrients, this being either by connection to a mammal body, or with a system of artificial circumfusion or with a system of perfusion supplying the required nutrients.
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