REMEDIES FOR SEPSIS

摘要

Remedies for sepsis and symptoms associating sepsis (septic shock, disseminated intravascular coagulation syndrome, adult respiratory distress syndrome, multiorgan function failure, etc.). These remedies contain as the active ingredient opioid kappa receptor agonistic compounds such as (-)-17-(cyclopropylmethyl)-3,14ss-dihydroxy-4,5a-epoxy-6ss [N-methyl-trans-3-(3-furyl)acrylamido]morphinan hydrochloride. These opioid kappa receptor agonistic compounds may be orally or parenterally administered either as such or as in the form of medicinal compositions prepared by mixing with publicly known pharmacologically acceptable acids, carriers, excipients, etc.