发明名称 Fluorinated polyenes
摘要 9-substituted, 4- or 6-fluorine substituted retinoic acid derivatives useful as antitumor agents and in the treatment of acne as well as a method for their manufacture are disclosed. Substituents at the 9-position include substituted phenyl, thienyl and furyl groups.
申请公布号 US4299995(A) 申请公布日期 1981.11.10
申请号 US19800149389 申请日期 1980.05.13
申请人 HOFFMANN-LA ROCHE INC. 发明人 CHAN, KA-KONG;PAWSON, BEVERLY A.
分类号 C07C41/16;C07C41/26;C07C41/48;C07C43/23;C07C43/315;C07C45/29;C07C45/41;C07C45/45;C07C59/58;C07D307/12;C07D307/16;C07D333/16;C07D333/22;C07D333/24;(IPC1-7):C07C43/02;C07C33/46;A61K31/09;A61K31/05 主分类号 C07C41/16
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