发明名称 |
Therapeutic process employing amides of L and DL phenylglycines |
摘要 |
Derivates of L- and DL-hydroxyphenylglycines of the formula <IMAGE> (II) and the pharmaceutically acceptable salts thereof, wherein R is hydrogen or methyl, R1 is hydrogen, amino or alkoxy having from one to six carbon atoms and R2 is the residue of certain alpha -amino acids are useful in treating diseases and conditions which are characterized by reduced blood flow, oxygen availability or carbohydrate metabolism in the cardiovascular system. Derivatives of D-hydroxyphenylglycine of formula (II) are substantially inactive in treating such diseases and conditions.
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申请公布号 |
US4299820(A) |
申请公布日期 |
1981.11.10 |
申请号 |
US19800126104 |
申请日期 |
1980.02.29 |
申请人 |
PFIZER INC. |
发明人 |
BARNISH, IAN T.;CROSS, PETER E.;DANILEWICZ, JOHN C. |
分类号 |
A61K38/00;A61P3/08;C07K5/06;C07K5/065;(IPC1-7):A61K37/00;A61K31/24 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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