发明名称 CHOLINE SALT CRYSTAL OF AZULENE COMPOUND
摘要 A choline salt crystal of (1S)-1,5-anhydro-1-[5-(azulen-2-ylmethyl)-2-hydroxyphenyl]-D-glucitol which shows an endothermic peak at 194 to 198‹C as measured by differential scanning calorimetry (DSC analysis) and shows main peaks at about 2Theta(‹) 5.58, 14.72, 16.80, 17.82, 21.02 and 22. 46 as measured by powder X ray diffraction. Thus, a crystal of an azulene compound can be produced which is in the form of a single crystal, has a fixed quality, can be produced with good reproducibility, can be provided stably as a crystal of an active substance for use in the preparation of a pharmaceutical and is excellent in storage stability. ® KIPO & WIPO 2008
申请公布号 KR20080023734(A) 申请公布日期 2008.03.14
申请号 KR20087000993 申请日期 2008.01.14
申请人 ASTELLAS PHARMA INC.;KOTOBUKI PHARMACEUTICAL CO., LTD. 发明人 IMAMURA MASAKAZU;SUZUKI TAKAYUKI;MURAKAMI TAKESHI;NAKANISHI KEITA;UEBAYASHI HIROSHI;NAKAMURA HARUKA;YUDA MASAMICHI;AMENOMIYA NAOKO;AWAMURA YUUJI;TOMIYAMA HIROSHI
分类号 C07H15/12;A61K31/704;A61P3/10 主分类号 C07H15/12
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