| 摘要 |
<p>Processes and intermediates for the total synthesis of 1-carbapenem antibiotics (I) via intermediates (III) and (IV): <CHEM> wherein R is hydrogen, a pharmaceutically acceptable ester moiety or salt cation, or a readily removable blocking group; R<6>, R<7> and R<8> are, inter alia, independently selected from the group consisting of hydrogen, alkyl, alkenyl, aryl and aralkyl, and X is a conventional leaving group.</p> |
