| 摘要 |
A composition is provided to be useful as an inhibitor of SNARE(soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex formation by controlling release of a neurotransmitter, thereby being applicable as a pain alleviating composition. A composition for mitigating pain comprises 0.001-50 wt.% of an extract of one natural material selected from the group consisting of leaves, flowers and stems of Carpinus tschonoskii; spikes of Platycarya strobilacea and Meliosma myriantha; aerial whole plants of Sedum kamtschaticum and Potentilla cryptotaeniae; stems of Euscaphis japonica and Juglans sinensis; roots of Boehmeria nivea; leaves of Schizophragma; flowers of Castanea crenata; and leaves and stems of Maackia amurensis, Elaeagnus umbellata, Rhus chinensis, Lindera erythrocarpa, Rubus crataegifolius, Cornus kousa, and Robinia pseudo-accacia, and a pharmaceutically acceptable carrier, diluent or excipient.
|
