发明名称 EPOXIDE INTERMEDIATE IN THE TAMIFLU SYNTHESIS
摘要 The present invention relates to technology for preparing derivatives of unsaturated, cyclic, organic acids and salts, thereof. Shikimic acid is an example of such an acid. More particularly, the present invention relates to preparing derivatives of these acids or salts thereof that are esterified, ketalized, functionalized with a leaving group, and/or provided with epoxide functionality. Preferred aspects may be used in the synthesis of Oseltamivir Phosphate starting from shikimic acid.
申请公布号 KR20080085061(A) 申请公布日期 2008.09.22
申请号 KR20087018410 申请日期 2008.07.25
申请人 F. HOFFMANN-LA ROCHE AG 发明人 GABEL RICHARD A.;GROANING MICHAEL D.;JOHNSTON DAVID A.
分类号 C07C67/08;C07C69/757;C07C309/66 主分类号 C07C67/08
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