| 摘要 |
There are described compounds of formula I, <IMAGE> I in which R3 represents hydrogen, or alkyl C 1 to 6, RS represents hydrogen, hydroxy, alkoxy C 1 to 6, alkanoyloxy C 2 to 6, alkenyloxy C 2 to 6, nitro, -NR1R2, halogen, alkyl C 1 to 6, hydroxy-alkyl C 1 to 6, or hydroxy-alkoxy C 1 to 6, an adjacent pair of X, Y and Z form a -(CH2)4-, -CH=CH-CH=CH- or -O(CH2)3- chain, each of the chains optionally being substituted by one or two C 1 to 6 alkyl groups, and the remaining substituent X or Z represents alkenyl C 2 to 6 optionally substituted by phenyl; halogen; or alkyl C 1 to 9 optionally substituted by one or more of the groups hydroxy, halogen, carbonyl oxygen, phenyl, or alkoxy C 1 to 6, or, when an adjacent pair of X, Y and Z form a chain substituted by one or two C 1 to 6 alkyl groups, the remaining substituent X or Z may be hydrogen, and R1 and R2, which may be the same or different, are each hydrogen or alkyl C 1 to 6, and pharmaceutically acceptable derivatives thereof. Processes for making the compounds and pharmaceutical, e.g. anti-allergic, compositions containing the compounds are also described. |
