发明名称 |
USE OF 4-[(4-THIAZOLYL)PHENOXY]ALKOXY-BENZAMIDINE DERIVATIVES FOR TREATMENT OF OSTEOPOROSIS |
摘要 |
This invention relates to a pharmaceutical composition containing 4-[(4-thiazolyl)phenoxyl]alkoxy-benzamidine derivatives expressed by the following formula 1 for the prevention and treatment of osteoporosis and more particularly, to the use of 4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl)phenoxyl]pentoxy}-benzamidine or N-hydroxy-4-{5-[4-(5-iso-propyl-2-methyl-1,3-thiazol-4-yl)phenoxyl]pentoxy}-benzamidine expressed by the following formula 1, which is known as an antagonist of leukotriene-B4 receptor, as a pharmaceutical composition for the prevention and treatment of osteoporosis. [Formula 1], wherein, R is a hydrogen atom or a hydroxy group. |
申请公布号 |
HK1069771(A1) |
申请公布日期 |
2009.04.24 |
申请号 |
HK20050102272 |
申请日期 |
2005.03.15 |
申请人 |
DONG WHA PHARM.IND.CO., LTD. |
发明人 |
HONG-SUK SUH;JIN-SOO LEE;PAN-SOO KIM;YUN-HA HWANG;JEI-MAN RYU;YONG-HO CHUNG;EUN-JOO KIM;DO-HUI KIM;YONG-YOUP PARK |
分类号 |
C07D277/24;A61K;A61K31/095;A61K31/426;A61P;A61P9/10;A61P19/10;A61P43/00 |
主分类号 |
C07D277/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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