发明名称 |
STABLE CRYSTAL OF ?-LACTAM COMPOUND |
摘要 |
<p>A stable crystal (I-form crystal) of (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-3-({4-[(5S)-5- methyl-2,5-dihydro-1H-pyrrol-3-yl]-1,3-thiazol-2-yl}thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid that has desirable characteristics as the active ingredient of drugs, and a method of producing the I-form crystal characterized by comprising desolvating the solvated crystal of the above compound.</p> |
申请公布号 |
WO2009075323(A1) |
申请公布日期 |
2009.06.18 |
申请号 |
WO2008JP72504 |
申请日期 |
2008.12.11 |
申请人 |
DAINIPPON SUMITOMO PHARMA CO., LTD.;YOKOYAMA, TATSUO;ITOH, MASANORI;TAKAMOTO, KOJI |
发明人 |
YOKOYAMA, TATSUO;ITOH, MASANORI;TAKAMOTO, KOJI |
分类号 |
C07D477/00;A61K31/427;A61P31/04;C07D487/04 |
主分类号 |
C07D477/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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