发明名称 GLYCOPROTEIN, ITS PREPARATION, ITS USE FOR THE MANUFACTURE OF ANTISERUM AND THE ANTISERUM
摘要 <p>A new glycoprotein is characterized by a protein consisting essentially of 75+/-6% of alpha -amino-acids, a carbohydrate portion of 24.6+/-5.2%, which contains 8.9+/-2% of hexoses, 7.1+/-1.5 of N-acetylated hexosamine, 0.2+/-0.2% of fucose, 8.4+/-1.5% of, N-acetylated neuraminic acid; a sedimentation coefficient S20w of 2.5+/-0.3 S; a molecular weight of 35,000+/-5,000, determined in the ultracentrifuge, and a molecular weight of 65,000+/-10,000, determined in polyacrylamide gel containing sodium dodecyl sulfate; an iso-electric point at pH 3.4+/-0.4; an extinction coefficient E11%cm (280 nm) of 1.9+/-0.3; an electrophoretic mobility in the range between that of alpha 1 and alpha 2-globulins; and a specific immunologic reaction with an antibody specifically directed against the glycoprotein.</p>
申请公布号 EP0000134(B1) 申请公布日期 1981.10.28
申请号 EP19780100134 申请日期 1978.06.09
申请人 BEHRINGWERKE AKTIENGESELLSCHAFT 发明人 BOHN, HANS, DR.;WINCKLER, WILHELM
分类号 G01N33/53;A61K38/16;A61K39/00;C07K1/22;C07K14/00;C07K14/47;C07K16/18;(IPC1-7):07G7/00;01N33/48 主分类号 G01N33/53
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