发明名称 Inhibitors of mammalian collagenase
摘要 Mammalian collagenase is inhibited by compounds having the formula <IMAGE> and salts thereof, wherein R1 is hydrogen or alkanoyl of 2 to 10 carbon atoms; R2 is hydroxy, amino, or <IMAGE> R3 is hydrogen, alkyl of 1 to 4 carbon atoms, <IMAGE> R4 is hydroxy, amino, arginine, leucine, glutamine, alanine or glycine; and m is 0 or an integer of 1 to 9.
申请公布号 US4297275(A) 申请公布日期 1981.10.27
申请号 US19800121352 申请日期 1980.02.14
申请人 E. R. SQUIBB & SONS, INC. 发明人 SUNDEEN, JOSEPH E.;DEJNEKA, TAMARA
分类号 A61K38/00;C07C51/08;C07C51/367;C07C51/377;C07C51/58;C07C317/04;(IPC1-7):C07C103/52;C07G7/00;C07C147/02 主分类号 A61K38/00
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