发明名称 PROCESS FOR THE PREPARATION OF 1-((1-METHYLETHYL)AMINO)-3-(((4-ALKYLTHIO)-1-NAPHTHALENYL)OXY)-2-PROPANOL
摘要 Title compds.[I; R = C1-3 alkyl were prepd. by treating 4-(alkylthio) - 1 - naphthols [compd. II with epichlorthydrin in the presence of basic ion-exchange resin, followed by amination with isopropylamine. The product is more lipophilic, a stronger vasodilator, a more selective β-adrenergic blocking agent on vascular β-receptors, and gave lower tachycardia than propranolol.
申请公布号 KR810001700(B1) 申请公布日期 1981.10.27
申请号 KR19790000778 申请日期 1979.03.15
申请人 WALLE T 发明人 WALLE T
分类号 (IPC1-7):C07C149/36 主分类号 (IPC1-7):C07C149/36
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