| 摘要 |
PURPOSE:To collect the titled substance from a culture, by cultivating a variant strain resistant to a methionine antimetabolite of a microorganism, belonging to Serratia marcescens, and having the ability to produce L-threonine. CONSTITUTION:A variant strain resistant to a methionine antimetabolite of a microorganism, belonging to Serratia marcescens, and having the ability to produce L-threonine, e.g. P-103 strain of Serratia marcescens Sr 41 (FERM-P No.5413), is cultivated in a culture fluid containing a carbon source, e.g. glucose, a nitrogen source, an organic nutrient, etc. The L-threonine produced and accumulated in the culture fluid is collected by the conventional separating and purifying operation with an ion exchange resin. |
