发明名称 |
Method for the preparation of cis-alkenyl bromide and acetate. |
摘要 |
A novel and improved synthetic route for the preparation of several kinds of cis-alkenyl acetates of the formula RCH=CHCH2CH2(CH2)nOCOCH3, in which R is an alkyl group having from 1 to 8 carbon atoms and n is a positive integer from 1 to 10, which compounds are known as sexual pheromone compounds of various noxious insects utilizable as a powerful means for the extermination of the insects, is proposed. The inventive method comprises cross coupling reaction of a Grignard reagent of a cis-alken-3-yl chloride of the formula RCH=CHCH2CH2Cl with an alpha , omega -dibromoalkane of the formula Br(CH2)nBr to form a cis-alkenyl bromide of the formula RCH=CHCH2(CH2)nBr which is further reacted with an alkali metal acetate. |
申请公布号 |
EP0038052(A1) |
申请公布日期 |
1981.10.21 |
申请号 |
EP19810102780 |
申请日期 |
1981.04.10 |
申请人 |
SHIN-ETSU CHEMICAL CO., LTD. |
发明人 |
YAMAMOTO, AKIRA;ISHIHARA, TOSHINOBU;TAGUCHI, KENICHI |
分类号 |
C07C17/26 |
主分类号 |
C07C17/26 |
代理机构 |
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