Method for the preparation of penicillanic- beta -lactamase inhibitors

摘要

In vivo hydrolyzable esters of 6 beta -bromopenicillanic acid when substantially free from the corresponding in vivo hydrolyzable ester of 6 alpha -bromopenicillanic acid is useful for their beta -lactamase inhibitory activity and may be administered either per se or in combination with a penicillin or cephalosporin.