| 摘要 |
<p>This invention is directed to compounds of the formula <IMAGE> or a physiologically acceptable salt thereof, wherein R is hydrogen or lower alkyl, R1 and R3 are independently selected from the group consisting of hydrogen, lower alkyl, lower alkylthio, -(CH2)n-SH, and halo substituted lower alkyl; R2 is hydrogen or lower alkyl provided that R2 is lower alkyl only when R1 is lower alkyl; m is zero, one or two; n is one, two or three; p and q are each one or two provided that both are not two; and R4 is hydrogen, a hydrolyzably removable protecting group, a chemically removable protecting group, or provided that neither R1 nor R3 is -(CH2)n-SH, <IMAGE> which are useful in the treatment of hypertension.</p> |
