发明名称 derivados de triazol e seu uso para transtornos neurológicos
摘要 The present invention is concerned with novel triazole compounds of formula (I) wherein A, X, Y, Z, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of present invention have affinity and selectivity for the GABA A α5 receptor. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.
申请公布号 BR112013011610(A2) 申请公布日期 2016.08.09
申请号 BR20131111610 申请日期 2011.11.07
申请人 F. HOFFMANN-LA ROCHE LTD 发明人 ANDREW THOMAS;MARIA-CLEMENCIA HERNANDEZ;MATHEW C. LUCAS
分类号 C07D401/12;A61K31/4192;A61K31/4439;A61K31/497;A61P25/00;C07D403/10;C07D403/12;C07D403/14;C07D405/14;C07D409/14;C07D413/14;C07D471/04;C07D491/107 主分类号 C07D401/12
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