| 发明名称 |
Composiciones de arní de serpina1 y sus métodos de uso |
| 摘要 |
The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the Serpina1 gene, and methods of using such RNAi agents to inhibit expression of Serpina1 and methods of treating subjects having a Serpina1 associated disease, such as a liver disorder. |
| 申请公布号 |
CL2015003441(A1) |
申请公布日期 |
2016.08.19 |
| 申请号 |
CL20150003441 |
申请日期 |
2015.11.23 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC |
发明人 |
MANOHARAN MUTHIAH;MAIER MARTIN;CHARISSE KLAUS;BETTENCOURT BRIAN;SEHGAL ALFICA;RAJEEV KALLANTHOTTATHI G.;HINKLE GREGORY |
| 分类号 |
A61K31/712;A61K31/713;A61P1/16;A61P11/00;C12N15/113 |
主分类号 |
A61K31/712 |
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