发明名称 MANUFACTURE OF IMIDAZOLE DERIVATIVE
摘要 The present invention relates to a novel process for preparing 4-¢(2-aminoethyl)thiomethyl!-5-methyl imidazole of the formula I and its acid addition salts, characterized as a process for preparing 4-¢(2-aminoethyl)thiomethyl!-5-methyl imidazole of the formula and its acid addition salts, characterized in that a compound of the formula wherein M represents hydrogen or an alkali metal, is reacted with a 2-haloethylamine, wherein halo represents chloro or bromo, in a system consisting of an aqueous solution or a strong base and of an organic phase, at room temperature in the presence of quaternary ammonium or quaternary phosphonium salts as phase transfer catalysts.
申请公布号 JPS56127361(A) 申请公布日期 1981.10.06
申请号 JP19810002751 申请日期 1981.01.13
申请人 LEK TOVARNA FARMACEVTSKIH 发明人 BURANKO IENKO;IGOORU RANGOFU
分类号 C07D233/64;B01J31/00;B01J31/02;C07B61/00;C07D;C07D233/54;C07D233/61 主分类号 C07D233/64
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