发明名称 Derivatives of A-30912A nucleus
摘要 Compounds of the formula <IMAGE> wherein R1 is a group of the formula: <IMAGE> (a) <IMAGE> (b) <IMAGE> (c) wherein A is divalent oxygen, sulfur, sulfinyl, or sulfonyl; A1 is divalent oxygen, sulfur, sulfinyl, sulfonyl or -NH-; X is hydrogen, chloro, bromo, iodo, nitro, C1-C3 alkyl, hydroxy, C1-C3 alkoxy, mercapto, C1-C3 alkylthio, carbamyl or C1-C3 alkylcarbamyl; X1 is chloro, bromo or iodo; R2 is hydrogen, C1-C18 alkyl or C2-C18 alkenyl; W is C1-C10 alkylene or C2-C10 alkenylene; m, n and p are 0 or 1, but if m=0, n must=0; provided: that the sum of the carbon atoms in the R2 and W groups must be greater than 4 but cannot exceed 21; that when X is mercapto. A and A1 cannot be sulfinyl or sulfonyl; and that when A and A1 are sulfinyl or sulfonyl, they must be in equal oxidation states.
申请公布号 US4293489(A) 申请公布日期 1981.10.06
申请号 US19800181442 申请日期 1980.08.25
申请人 ELI LILLY AND COMPANY 发明人 DEBONO, MANUEL
分类号 A61K38/00;C07K7/56;(IPC1-7):C07C103/52 主分类号 A61K38/00
代理机构 代理人
主权项
地址