摘要 |
Phenoxypropylamine derivatives of the general formula <IMAGE> (I) wherein R1 represents a hydrogen atom or a methyl or ethyl group, R2 and R3, independently from each other, represent a lower alkyl group, or together form a linear alkylene group having 4 to 7 carbon atoms which may be optionally substituted by a hydroxyl or hydroxymethyl group, and R4 represents a hydrogen atom or a group of the formula -R5-Z in which R5 represents a lower alkylene group, and Z represents a hydrogen atom or an amino, mono- or di-(lower alkyl)-amino, hydrdoxy lower alkylamino, lower alkanoylamino, hydroxyl, lower alkoxy, lower alkanoyloxy, phenoxy, halophenoxy, benzoyloxy or halobenzoyloxy group, and the salts thereof; to a process for production thereof; and to their medicinal use, particularly to antiulcer agents comprising these phenoxypropylamine derivatives or their salts.
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申请人 |
TEIKOKU HORMONE MFG. CO., LTD. |
发明人 |
SHIBATA, KENYU;ITAYA, TOSHIHISA;YAMAKOSHI, NOBUAKI;KURATA, SHIGERU;KOIZUMI, NAOYUKI;TARUTANI, MASAAKI;SAKUMA, HIDEKI;KONISHI, KUNIHIRO |