摘要 |
NEW MATERIAL:An amino sugar compound expressed by the formula (m is an integer 1-8). For example, a compound of the formula (m is 1) has the following physico-chemical proPerties: Molecular formula: C19H33O14N. Molecular weight: 499. Elementary analysis: C, 45;6%; H, 6.68%; O, 44.80%; N, 2.83%. [alpha]D<22>=+ 50+ or -4 (water, C-0.5). Decomposition point: 135-150 deg.C. Soluble in water, dimethyl sulfoxide, methanol and pyridine; insoluble in acetone, chloroform, etc. Positive to the anthrone, Molisch and iodine reactions; negative to the Sakaguchi and biuret reactions. USE:An inhibitor capabLe of inhibiting the activity of glcosidase, e.g. amylase, maltase or sucrase, specifically. PROCESS:Streptomyces calvus varietas TM-521 strain (FERM-P No. 4283) is cultivated preferably by the aerobic liquid submerged culture method at pH6.6- 7 and 28-35 deg.C for 3 days to give the aimed compound. |