发明名称 |
Antitussive and analgesic di:glaucine phosphate - having no unpleasant flavour, suitable for oral admin. |
摘要 |
<p>d-Glaucine phosphate (I) is new. It is an antitussive agent with an oral ED50 of 170.1 mg/kg and analgesic. Its lack of a bitter taste makes it much simpler to administer than the free alkaloid. (I) is prepd. by treating d-glaucine with at least 1/4 molar excess of phosphoric acid. This may be effected in an inert organic solvent such as acetone, ethanol, chloroform etc.</p> |
申请公布号 |
NL8001203(A) |
申请公布日期 |
1981.10.01 |
申请号 |
NL19800001203 |
申请日期 |
1980.02.28 |
申请人 |
THE DOW CHEMICAL COMPANY TE MIDLAND, MICHIGAN, VER. ST. V. AM. |
发明人 |
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分类号 |
C07D221/18;(IPC1-7):07D221/18;61K31/485 |
主分类号 |
C07D221/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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