发明名称 PROCEDEU PENTRU PREPARAREA UNOR 2-(4-ARILPIPERAZIN-1-IL)-4-AMINO-6,7-DIMETOXICHINAZOLINE
摘要 <p>Certain 2-(4-aroylpiperazin-1-yl)-4-amino-6,7-dimethoxyquinazolines are prepared by a novel process wherein certain 2-(4-substituted-piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline intermediates wherein said substituent is cyano, certain carbon-oxygen double bond containing groups or certain carbon-nitrogen double bond containing groups, are reacted with certain metalloaryl compounds followed by hydrolysis. The products are known hypotensive agents. Certain of the process intermediates are novel compounds.</p>
申请公布号 RO73051(A) 申请公布日期 1981.09.24
申请号 RO19770091610 申请日期 1977.09.19
申请人 PFIZER INC,US 发明人 HAMMEN,PHILIP D.,US
分类号 C07D403/04;A61K31/505;A61K31/517;A61P9/12;C07D239/95;C07D307/56;(IPC1-7):07D239/86 主分类号 C07D403/04
代理机构 代理人
主权项
地址