发明名称 CYANOALKYLUREIDO CEPHALOSPORINS
摘要 <p>Cyanoalkylureido cephalosporins of the formula wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, diphenyl-lower alkyl, tri(lower alkyl)silyl, trihaloethyl, a salt forming ion, or the group ; R1 is hydrogen or methoxy; A is straight or branched chain alkylene or ; R2 is phenyl, 2-thienyl, or 3-thienyl; R3 is hydrogen or lower alkyl; R4 is hydrogen, lower alkyl, cycloalkyl, cycloalkenyl, cycloalkadienyl, phenyl, phenyl-lower alkyl, substituted phenyl, substituted phenyl-lower alkyl, or certain heterocyclic groups; R5 is hydrogen or lower alkyl: R6 is lower alkyl; and X is hydrogen, lower alkanoyloxy, , , or certain heterothio groups; are disclosed. These compounds are useful as antibacterial agents.</p>
申请公布号 CA1109460(A) 申请公布日期 1981.09.22
申请号 CA19770271523 申请日期 1977.02.10
申请人 SQUIBB (E. R.) & SONS, INC. 发明人 BREUER, HERMANN;TREUNER, UWE D.
分类号 A61K31/545;A61K31/546;A61P31/04;C07D333/24;C07D501/20;C07D501/36;(IPC1-7):07D501/20 主分类号 A61K31/545
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