Esters of 2-vinylclav-2-em-3-carboxylic acid and process for preparing same
摘要
2-Vinylclavem compounds are disclosed which have been found of value in the synthesis of thio-derivatives of clavulanic acid which possess antibiotic and beta -lactamase inhibitory activity. Methods for preparing the vinylclavem compounds are disclosed and processes for preparing the thio-derivatives are given.
申请公布号
US4290949(A)
申请公布日期
1981.09.22
申请号
US19770809915
申请日期
1977.06.24
申请人
GLAXO OPERATIONS UK LIMITED
发明人
CHERRY, PETER C.;NEWALL, CHRISTOPHER E.;WATSON, NIGEL S.;GREGORY, GORDON I.;WARD, PETER