发明名称 PREPARATION OF POLYMER COMPOSITION INCLUDING PHYSIOLOGICALLY ACTIVE SUBSTANCE
摘要 PURPOSE:To make a polymer composition including a physiologically active substance in high activity, by polymerizing a system consisting of one or more physiologically active substance, a protecting substance for it, glutaraldehyde, and a vinyl type polymerizable monomer at a specific temperature range for a given time. CONSTITUTION:A small amount of glutaraldehyde is added to a mixed solution of one or more vinyl polymerizable monomers, e.g., ethylene glycol diacrylate, etc. and a protecting substance, e.g., egg albumin, L-threonine, etc. for a physiologically active substance, to give a mixed solution. The mixed solution is added to a buffer solution which suspends or floats a physiologically active substance, e.g., an enzyme, mold, etc., and the prepared solution is allowed to stand for several hours and polymerized. Thus, a polymer composition including the physiologically active substance is prepared.
申请公布号 JPS56117792(A) 申请公布日期 1981.09.16
申请号 JP19800018788 申请日期 1980.02.18
申请人 JAPAN ATOMIC ENERGY RES INST 发明人 YOSHII FUMIO;KAETSU ISAO;FUJIMURA TAKU
分类号 C08F2/00;A61K9/00;A61K35/18;A61K35/407;A61K36/00;A61K38/46;C08F2/44;C08F20/10;C12N11/04;C12N11/08 主分类号 C08F2/00
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