发明名称 Process for the preparation of alkylsulphonylamino-containing cephem derivatives
摘要 7 beta -[D-2-Amino-2-(lower alkylsulphonylaminophenyl)acetylamino]-3-R-3-cephem-4-carboxylic acids of the formula I in which R is halogen, preferably chlorine, or lower alkoxy, preferably methoxy, are prepared. The process is based on sulphonation of the free amino group on the phenyl ring of corresponding 7 beta -(D-2-amino-2-aminophenylacetylamino)-3-R-3-cephem-4-carboxylic acids. The compounds are active against both Gram-positive and Gram-negative bacteria. <IMAGE>
申请公布号 CH625247(A5) 申请公布日期 1981.09.15
申请号 CH19800004330 申请日期 1980.06.04
申请人 CIBA-GEIGY AG 发明人 DR. RENE WIEDERKEHR;DR. HANS BICKEL
分类号 C07D501/59;(IPC1-7):C07D501/59 主分类号 C07D501/59
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