发明名称 |
PROCESS FOR THE PREPARATION OF 3-BROMOMETHYL-3-CEPHEM-SULPHOXIDE DERIVATIVES |
摘要 |
<p>Improved process for the preparation of brominated cephalosporanic derivatives, wherein a desacetoxy-3-cephem sulphoxide of general formula …<CHEM>… wherein R1 represents an acylamido group and R2 represents a group protecting the carboxy radical, is brominated in manner known per se and a compound of general formula …<CHEM>… in the reaction mixture or separated from such a reaction mixture is debrominated in the presence of a hydrogen donor and the 3-bromomethyl-3- cephem derivative of the general formula …<CHEM>… thus produced is recovered.</p> |
申请公布号 |
DE2860746(D1) |
申请公布日期 |
1981.09.10 |
申请号 |
DE19782860746 |
申请日期 |
1978.09.06 |
申请人 |
GIST - BROCADES N.V. |
发明人 |
BRUYNES, CORNELIS ADRIANUS;DE KONING, JAN JACOBUS |
分类号 |
A61K;C07D;C07D501/00;C07D501/02;C07D501/04;C07D501/22;C07D501/24;C07F7/18;(IPC1-7):07D501/24;07D501/00 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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