发明名称 QUINONE COMPOUND AND ITS PREPARATION
摘要 NEW MATERIAL:A quinone compound of formula I (n is an integer of 1-10; R<1> is methyl, methoxy, or two R<1> together form -CH=CH-CH=CH-; R<2> is lower alkyl), or its hydroquinone. USE:Hypotensor, analgesic antiulcer agent, antiphlogistic agent, diuretic, immune regulator, antiasthmatic agent, antiallergic agent, antithrombic agent, cerabral circulation improving agent, etc., having low toxicity. PROCESS:The compound of formula I is prepared by removing the protection group (e.g. by hydrolysis, oxidative removal of the protection group, etc.) of the compound of formula II (R<3> is protection group such as 1-3C alkyl, 1-3C alkoxymethyl, 2-4C alkanoyl, etc.), and if necessary, oxidizing the product.
申请公布号 JPS56113731(A) 申请公布日期 1981.09.07
申请号 JP19800016455 申请日期 1980.02.12
申请人 TAKEDA CHEMICAL INDUSTRIES LTD 发明人 TERAO SHINJI;SHIRAISHI MITSURU;NISHIKAWA KOUHEI
分类号 A61K31/045;A61K31/12;A61K31/122;A61P7/10;A61P25/00;A61P37/00;C07C27/00;C07C39/19;C07C45/00;C07C50/38;C07C67/00 主分类号 A61K31/045
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