发明名称 |
Salts of erythromycin A esters and preparation process. |
摘要 |
<p>High water-soluble erythromycin A derivatives wherein the desosamine moiety is quaternized with an acyloxy-, benzoyloxy- or alkoxycarbonyl-(or carboxy)-acylmethyl iodide, bromine or chloride and esterified in the 2-position with loweralkyl or -(CH2)nCO2R sec , wherein R sec is H, loweralkyl or substituted loweralkyl and n is an integer from 1-5. These new esters readily convert to erythromycin A upon administration to warm-blooded animals. </p> |
申请公布号 |
EP0034700(A1) |
申请公布日期 |
1981.09.02 |
申请号 |
EP19810100290 |
申请日期 |
1981.01.16 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
BODOR, NICHOLAS S.;FREIBERG, LESLIE ALAN |
分类号 |
A61P31/04;A61K31/70;A61K31/7042;A61K31/7048;C07H17/08;(IPC1-7):07H17/08;61K31/70 |
主分类号 |
A61P31/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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