UN PROCEDIMIENTO PARA LA PREPARACION DE (6R,7R)-7-((Z)-2- (2-AMINOTIAZOL-4-IL)-2-(2-CARBOXIPROP-2-OXIIMINO)ACETAMI- DO)-3-(1-PIRIDINIOMETIL)CEF-3-EM-4-CARBOXILATO PENTAHIDRATA-DO

摘要

(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(2-carboxyprop-2-oxyimino)ace tamido]-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate in the form of its crystalline pentahydrate. This pentahydrate has a well defined crystalline structure and exhibits good stability on storage. The pentahydrate exhibits excellent antibiotic activity, particularly against organisms which are normally difficult to combat with beta -lactam antibiotics.