发明名称 |
METHOD OF PREPARATION OF THE 1,4,3,6-DIANHYDRO-D-GLUCITOL-2-NITRATE |
摘要 |
The following process for preparing 1,4:3,6-dianhydro-D-glucitol 2-nitrate is described: acylating 1,4:3,6-dianhydro-D-glucitol with 0.5 to 1.5 molar equivalents of acetic anhydride in the presence of an acid catalyst, nitrating the product so obtained with a mixture of nitric acid and acetic anhydride, hydrolyzing the product so obtained in the presence of an inorganic base and isolating 1,4:3,6-dianhydro-D-glucitol 2-nitrate. The 1,4:3,6-dianhydro-D-glucitol 2-nitrate is useful as a coronary vasodilator. |
申请公布号 |
CS208199(B2) |
申请公布日期 |
1981.08.31 |
申请号 |
CS19770006765 |
申请日期 |
1977.10.18 |
申请人 |
AMERICAN HOME PRODUSTS CORP.,US |
发明人 |
CHOU,CHIH H.,CA;MYERS,GORDON S.,CA |
分类号 |
C07D493/04;(IPC1-7):C07H11/02 |
主分类号 |
C07D493/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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