Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them.

摘要

The present invention provides the compounds of the formula (II):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="21" wi="59" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>and pharmaceutically acceptable salts and cleavable esters thereof wherein RCONH is an organic acylamino group and E is a carboxy group or pharmaceutically acceptable salt or ester thereof or is a cyano group. Their preparation is described as is their use in compositions containing them. Compounds wherein RCONH is replaced by an azido group are described as useful intermediates.