| 摘要 |
<p>Title compds. [I; R = II(R1,R2,R3 = H, lower alkyl, R1 and R2 combined lower alkylene), III(X = amino, O, S; R4,R5,R6 = H, lower alkyl, R4 and R5 combined lower alkylene, lower alkenylene, O-phenylene, azo group), IV(R8 = H, lower alkyl; R9 = aralkyl, aralkylene, aryl), substituted phenyl; Ar = aryl; Y = H, methoxy; Het is 5 or 6 membered aromatic heterocycle which comprise 1-4 hetero atom such as N, O or S; Z = hydroxy, carboxy protecting group; W = reactive functional group , having antibacterial activity, were prepd. by acylatingα-amino group of compd. (V) with acylating agent(VI).</p> |
