| 摘要 |
<p>Process for the stereospecific reduction of amino-substituted indoles and indole-containing structures to trans-dihydroindoles comprising reacting the acid addition salt of an indole with a borohydride in an appropriate solvent, followed by reaction with a strong mineral acid. Many dihydroindiles so produces, for example, the trans-2-(adamantylmethyl)-2,3,4,4a,5?9b-= hexahydro-5-phenyl-1H-pyrido¢4,3-b!-indole, are useful as pharmaceutical materials, such as tranquilizers.</p> |
