摘要 |
<p>The present invention provides a proccss for the preparation of a nucleoside from a nucleoside base and a 1-o-acyl or 1-halogen derivative of a protected mono-, oligo- or polysaccharide or a 2-o-acyl, 2-o-alkyl or 2-halogen derivative of tetrahydrofuran or tetrahydropyran, wherein reaction is carried out in one step in the presence of a catalyst and silylation reagent.</p> |