| 摘要 |
PURPOSE:To prepare a hydrazone useful as a synthetic raw material of asymmetrically substituted hydrazine, by reacting a ketone, a primary amine, NH3, and a peroxide in the presence of a specific aromatic carbonate or alkylene carbonate. CONSTITUTION:A hydrazone of formula IV is prepared by reacting an aliphatic or alicyclic ketone of formula I (R<3> and R<4> are 1-4C alkyl; or R<3> and R<4> together form a ring containing carbonyl C), a primary amine of formula II (R<5> is phenyl, 1- 4C alkyl, etc.), NH3, and a peroxide, in the presence of a carbonate of formula III (R<1> and R<2> are phenyl or alkylphenyl; or R<1> and R<2> are 1-4C alkylene and together form a ring containing carbonyl C). The reaction is pref. carried out in an alcohol such as isopropanol, at 40-80 deg.C. |
