发明名称 |
Imidazoline derivative, its salts, process for preparation and pharmaceutical compositions thereof. |
摘要 |
<p>2-[2-(1,4-Benzodioxanyl)]-2-imidazoline or a non-toxic salt thereof, substantially free of 2-methyl-2-[2-(1,-3-benzodioxolyl)]-2-imidazoline or non-toxic salt thereof.</p><p>2-[2-(1,4-Benzodioxanyl)]-2-imidazoline or a non-toxic salt thereof characterised in that the nuclear magnetic resonance spectrum of the compound in a protonated form exhibits multiplets in the region of τ 4.4 and τ 5.4.</p><p>Process for the preparation of 2-[2-(1,4-benz- odioxanyl)]-2-imidazoline, pharmaceutical compositions thereof or of its salts, and their use as presynaptic α<Sub>2</Sub>- adrenoreceptor antagonists.</p> |
申请公布号 |
EP0033655(A2) |
申请公布日期 |
1981.08.12 |
申请号 |
EP19810300427 |
申请日期 |
1981.02.02 |
申请人 |
RECKITT AND COLMAN PRODUCTS LIMITED |
发明人 |
CHAPLEO, CHRISTOPHER BOURNE;MYERS, PETER LESLIE |
分类号 |
C07D405/04;A61K31/415;A61K31/4178;A61P3/08;A61P7/10;A61P9/06;A61P9/12;A61P25/00;A61P25/02;A61P25/04;A61P25/24;A61P25/26;C07D319/20;C07D407/06;(IPC1-7):07D405/04;61K31/415 |
主分类号 |
C07D405/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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