PROCESSO PARA A OBTENCAO DE DERIVADOS DO ACIDO EPOXISUCCINIO

摘要

Novel epoxysuccinic acid derivatives are provided of the formula:- and non-toxic salts thereof, where R represents a lower alkyl group. These epoxysuccinic acid derivatives and their non-toxic salt are useful for inhibiting myocardial infarction. The derivatives may be made by reacting a leucine lower alkyl ester with a trans- epoxysuccinic acid mono-ester, or trans-epoxysuccinic acid itself.