发明名称 |
PREPARATION OF TRIS (HYDROXYMETHYL) AMINO METHANE |
摘要 |
Tris(hydroxymethyl)aminomethane, an intermediate of organic synthesis, in crystalline form is made by formylation followed by hydrogenation. Nitromethane and formaldehyde in a molar ratio on the order of 1:3 are reacted in a concentrated alcohol medium made up of a 2 to 5% mixture of methylene chloride in methanol, in the presence of 1 to 10 milliequivalents per mole of nitromethane of a solid base catalyst selected from sodium or potassium, with agitation for a period between 3 and 36 hours at a temperature below 50 DEG C. |
申请公布号 |
DE2960283(D1) |
申请公布日期 |
1981.08.06 |
申请号 |
DE19792960283 |
申请日期 |
1979.01.24 |
申请人 |
SOCIETE CHIMIQUE DE LA GRANDE PAROISSE AZOTE ET PRODUITS CHIMIQUES |
发明人 |
BOURGUIGNON, JEAN;SION, MARCEL-XAVIER;MOREAU, MICHEL |
分类号 |
C07C213/10;C07C;C07C67/00;C07C213/00;C07C215/12;(IPC1-7):C07C91/10;C07C89/00 |
主分类号 |
C07C213/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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