摘要 |
<p>The invention relates to a process for the preparation of ranitidine of formula (I> <IMAGE> which comprises reacting a thiol of formula (II> <IMAGE> with an alkylating agent of formula (III> <IMAGE> where R1 is the group -CH2CH2L, in which L is a leaving group, and R2 is a hydrogen atom, or R1 and R2, together with the nitrogen atom to which they are attached form an ethyleneimino group; and to intermediates for the said process.</p> |