2-AMINO-CYCLOPENT-1-ENE-1-DITHIOCARBOXYLIC ACID DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF

摘要

New 2-amino-cyclopent-1-ene-1-dithiocarboxylic acid derivatives of the general formula /I/, /I/ wherein R is a C2-4 alkenyl group, a C3-8 cycloalkyl group, phenyl group or a C1-6 alkyl group having optionally a C1-4 alkoxy, hydroxy, carboxy and/or amino substituent, with the proviso that if R is an unsubstituted alkyl group, this group contains at least 5 carbon atoms, are prepared by reacting 2-amino-cyclopent-1-ene-1-dithiocarboxylic acid or a salt thereof with an amine of the general formula /II/, R-NH2 /II/ wherein R is as defined above. The new compounds of the invention exert dopamine-.beta.-hydroxylase inhibiting effects.