发明名称 DIALUMINUM SALT OF NN*BETAA*N**ACYLAMINO*PROPIONYL* HISTIDINE AND ITS PREPARATION
摘要 NEW MATERIAL:Dialuminum salt of an N-[beta-(N'-acylamino)propionyl]histidine expressed by formula I (R is 1-6C alkyl, phenyl or 7-9C aralkyl). EXAMPLE:Dialuminum salt of N-[beta-(N'-acetylamino)propionyl]histidine. USE:A remedy for acute and chronic peptic ulcer with very low toxicity and high safety. PROCESS:An N-[beta-(N'-acylamino)propionyl]histidine of formula II is reacted with an aluminum alkoxide to give the compound of formula I.
申请公布号 JPS5692276(A) 申请公布日期 1981.07.25
申请号 JP19790168274 申请日期 1979.12.26
申请人 NIPPON CHEMIPHAR CO 发明人 MAZAKI MITSUO;YAMANAKA TOORU;YOSHIOKA MITSUKO;OKAI KAZUYOSHI
分类号 A61K31/415;A61K38/00;A61P1/04;C07D233/54;C07D233/64 主分类号 A61K31/415
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