发明名称 VACCINS CONTRE DES MALADIES PROVOQUEES PAR DES REOVIRUS ET PROCEDE DE PREPARATION DE CES VACCINS
摘要 <p>Vaccines derived from avian reo virus to combat aberations of the skeleton such as rachitis-like symptoms, osteoperose c.q. femur degeneration, diarrhoea and growth inhibition, a process for their preparation, combined, inactivated vaccines, ready for administration and active against at least Newcastle disease and disease symptomes caused by reo virus and process for the preparation of such vaccine, are disclosed. The combined vaccine is prepared by addition of a Newcastie disease virus (NDVl) containing liquid, obtained by cultivation of a NDV, followed by inactivation of this liquid and optionally homogenizing it, together with a reo virus-containing liquid, obtained by cultivation of a rea virus, followed by inactivation of this liquid and optionally homogenizing it, to an oily phase containing as essential components at least one of the components selected from the group consisting of light paraffinic mineral oils, plant oils and pafthenic mineral oils and one or more emulsifiers, such as non-ionic surface-active compound derived from alkylene oxide and/or hexahydric alcohols and/or higher natural fatty acids such as esters or ester-ethers, optionally followed by homogenizing and/or addition of a preservative. Also a reo virus strain LZ 671, deposited with the collection D'Institut Pasteur, Paris under no. I-092 is disclosed.</p>
申请公布号 LU82018(A1) 申请公布日期 1981.07.23
申请号 LU19790082018 申请日期 1979.12.20
申请人 GIST BROCADES NV 发明人 KRASSELT M;APONTOWEIL P
分类号 A61K39/15;A61K39/17;A61K39/295;C12N7/04;(IPC1-7):61K/;12N/ 主分类号 A61K39/15
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