摘要 |
<p>The present invention provides compounds of the general formula: <CHEM> wherein R<1> is an aryl, ar(lower)alkyl or pyridyl radical, each of which may be substituted by halogen, amino, lower alkyl, lower alkoxy or carboxy(lower)alkyl, R<2> is a hydrogen or halogen atom, R<3> is an amino, lower alkylamino, acylamino or nitro radical, R<4> is a divalent radical of the general formula -CnH2n- in which n is an integer of from 1 to 7, and A is oxy, thio, sulfinyl, sulfonyl or imino, the derivatives of the carboxy group, and the pharmaceutically acceptable salts thereof. <??>The present invention also provides processes for the preparation of these compounds, as well as pharmaceutical compositions containing them. </p> |