摘要 |
<p>Novel 4-(5- and 7-) benzoylindolin-2-ones are described having the formula wherein R is hydrogen or lower alkyl, R2 is hydrogen, fluorine, chlorine, bromine, iodine or lower alkoxy, Z is hydrogen or SCH3, and X and Y are the same or different and represent hydrogen atoms or lower alkyl, lower alkoxy, fluorine, chlorine, bromine, iodine, nitro or trifluoromethyl groups, or together form a lower alkylenodioxy group. The compounds are prepared from corresponding aminobenzophenones, istatins, or indolin-2-ones. The compounds are precursors in the production of 2amino-3-(5- and 6-) benzophenylacetic acids, esters, alkali metal salts and alkaline earth metal salts, which latter compounds exhibit pharmacological properties.</p> |