发明名称 PROCESS FOR PREPARING 1,4:3,6-DIANHYDRO-D-GLUCITOL 2- NITRATE
摘要 <p>PROCESS FOR PREPARING 1,4:3,6-DIANHYDRO-D-GLUCITOL 2-NITRATE The following process for preparing 1,4:3,6-dianhydro-D-glucitol 2-nitrate is described: acylating 1,4:3,6-dianhydro-D-glucitol with 0.5 to 1.5 molar equivalents of a lower alkanoic acid anhydride in the presence of an acid catalyst, nitrating the product so obtained with a mixture of nitric acid and acetic anhydride, hydrolyzing the product so obtained in the presence of an inorganic base and isolating 1,4:3,6-dianhydro-D-glucitol 2-nitrate. The 1,4:3,6dianhydro-D-glucitol 2-nitrate is useful as a coronary vasodilator.</p>
申请公布号 CA1103262(A) 申请公布日期 1981.06.16
申请号 CA19770287803 申请日期 1977.09.29
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 CHOU, CHIH H.;MYERS, GORDON S.
分类号 C07D493/04;(IPC1-7):07D493/04 主分类号 C07D493/04
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